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Absolute changes of LFC (%)
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Men
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Women
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Interaction test P value
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|---|
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Model 1
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β (95%CI)
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9.79 (0.37, 19.21)
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− 8.26 (− 17.18, − 0.65)
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0.003
|
|
P value*
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0.046
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0.025
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Model 2
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β (95%CI)
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8.42 (− 1.40, 18.23)
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− 8.19 (− 16.64, − 0.27)
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0.011
|
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P value*
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0.099
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0.033
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Model 3
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β (95%CI)
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5.25 (− 3.25, 18.76)
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− 7.75 (− 12.32, − 0.13)
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0.039
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P value*
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0.464
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0.045
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Model 4
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β (95%CI)
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6.09 (− 3.02, 15.20)
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− 5.25 (− 13.38, 2.88)
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0.024
|
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P value*
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0.193
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0.210
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Model 5
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β (95%CI)
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5.86 (− 3.24, 14.97)
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− 4.78 (− 13.43, 3.88)
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0.059
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P value*
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0.211
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0.283
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Model 6
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β (95%CI)
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6.98 (− 6.59, 14.54)
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− 3.33 (− 11.09, 4.44)
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0.291
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P value*
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0.801
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0.405
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- Data are shown as means (95% confidence interval). Absolute changes of LFC (%), difference of the absolute changes of LFC for men or women between the PGZ + LSI and LSI groups. Model 1: not adjusted; model 2: adjusted for age, smoking, drinking, baseline BMI, change of BMI, and treatment adherence; model 3: adjusted for baseline LFC and variables in model 2; model 4: adjusted for glucose metabolism and variables in model 2; model 5: adjusted for change of HOMA-IR and variables in model 2; model 6: adjusted for baseline LFC, glucose metabolism, change of HOMA-IR, and variables in model 2. Interaction test P value was assessed by Wald’s test
- LFC liver fat content
- *P value calculated by linear regression model, difference between the PGZ + LSI group and the LSI group
